scFv/Fab Construction

Creative Biolabs has established a solid platform for scFv and Fab construction. There are three routes to have a scFv or Fab targets a specific antigen. The first approach is to generate a mouse hybridoma clone, then convert full IgG (or IgM) into a scFv or Fab; the second approach is to create an immunized phage display scFv or Fab mouse library, then use the antigen to screen the library; the third method is to use the antigen to screen a premade scFv or Fab antibody phage display library (usually a human one) to get scFv or Fab clones directly. We are also able to convert chicken IgY into scFv or Fab fragments.