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car t cell design
address:45-1 Ramsey Road, Shirley,NY 11967,
Québec QC, H4N3M8tel:516-669-8109fax:employees: -
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BUSINESS DESCRIPTION
A chimeric antigen receptor (CAR) mainly consists of a single chain variable fragment (scFv) from a mAb, an extracellular hinge and spacer element, a transmembrane region (TM) and an internal signaling domain such as CD3? or Fc receptor ? cytoplasmic signaling domains (Fc?RI?). The main advantage of CAR modified T cell is that it decreases MHC restriction, which allows the adoptive immune cells to be directly activated in various types of cancers.FIND JOBS IN CANADA
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