t cell antibody production

Creative Biolabs provides anti-idiotypic antibody production service detecting T cell receptors. We utilize target TCR in scFv form or using a peptide designed according to the sequences of the variable domains as target to isolate anti-idiotypic antibodies from immunized phage diplay library. Anti-idiotypic antibodies could bind to idiotypes that were epitopes present in the variable regions of the receptors of both T and B lymphocytes, and each receptor carries a set of idiotopes that defines its unique idiotype.